Searchable abstracts of presentations at key conferences in endocrinology

ea0056p940 | Female Reproduction | ECE2018

Subchronic exposure to kalach 360 SL-induced endocrine disruption in female ovaryrats

Hamdaoui Latifa , Naifar Manel , Rahmouni Fatma , Ayedi Fatma , Sahnoun Zouheir , Abid Mohamed , Rebai Tarek

Kalach 360 SL (KL), glyphosate (G) surfactant-based herbicides, is a systemic herbicide effective against weeds. It was applied in agriculture in Tunisia and throughout the world, which can represent a risk to non-target organisms. The aim of this study was to investigate the morphological and biochemical aspects of ovary injury after exposure to KL. Female Wistar rats were divided into three groups: group 1 was used as a control; group 2 orally received 0.07 ml of KL, (126 mg...

ea0056ep144 | Reproductive Endocrinology | ECE2018

Endocrine disruption and oxidative stress implications of imipenem therapy in the ovary of ‘wistar’ rats

Tahri Amal , Naifar Manel , Daoud Salima , Kacem Faten Haj , Rebai Tarek , Ayedi Fatma , Abid Mohamed , Sahnoun Zouheir

Imipenem (IMP) is a carbapenem antibiotic mainly used to treat nosocomial infection diseases. We aimed to evaluate the oxidative stress of therapeutic doses of imipenem (IMP) on the ovary of ‘wistar’ rats. In this respect, female rats were divided into four groups: animals were intraperitoneally treated with physiological serum, 30, 50 and 80 mg/kg of IMP for one week. We found that therapeutic doses of this drug did not significantly affect the levels of ovarian mal...